

Respiratory Data from Home™
Scalable Platform for Real-time, High-quality, Remote Spirometry
Empowering respiratory trials with daily home-based monitoring, rich data, and seamless trial integration.
PHARMA FACES PERSISTENT CHALLENGES IN RESPIRATORY CLINICAL TRIALS WITH SPIROMETRY ENDPOINTS




9 out of 10 trials require onsite (at clinic) spirometry
In-person spirometry measurements result in a 30% intra-individual variability, increasing trial time, cost, and data requirements. 9 out of 10 trials require onsite (at clinic) spirometry causing logistic and scheduling conflicts exacerbating data collection- increased cost, inconvenience, more participants, and more visits to meet the statistical requirements-



Why Traditional Spirometry Fails

One data point per visit
The COPD patient population is underserved both for diagnosis and monitoring.
Limited access
patient must wait for appointment, drive to clinic, limited access to Respiratory Therapists (SME)
Higher Variability
up to 40% variability noted between visits
SCALABLE PLATFORM FOR REAL-TIME, HIGH-QUALITY, REMOTE SPIROMETRY
Although traditional, in-person spirometry is the gold standard, it is burdensome to patients and relies heavily on technician skill. Infrequent, in-person spirometry measurements result in a 30% intra-individual variability, increasing trial time, cost, and data requirements.
REMOTE SPIROMETRY, GUIDED BY CREDENTIALED RESPIRATORY THERAPISTS PRODUCES RELIABLE DATA SETS
ATS/ERS
The skill gap of staff performing spirometry in clinical trials reduces adherence to global quality standards (ATS/ERS)
40%
Real time Respiratory Therapists coaching reduces variability by up to 40% through the PulManage platform
More Data
Spirometry collection in the home generates more frequent and consistent data than on site


PulManage Data is Rich
Not Just Spirometry Data

Also, real-world data from wearables and PROs

We can contextualize the spirometry data which makes it more impactful and acomplete picture of the patient journey

Our Mission
To make respiratory clinical trials faster, smarter, and more accessible through innovative technology, patient-first design, and clinical-grade data collection at scale.


Serving All Trial Phases and Real World Studies
Patient Benefits:
- Improves access, convenience, & experience
- Enables real-time monitoring with personalized support and insights
sponsor benefits
- Richer data
- Reduces variability
- Cleaner trial outcomes
- Scalable data integration API
Trial logistics
- Accelerates timelines
- Broader patient access
- Supports smaller, more efficient studies
- Scales with trial growth
Our Partners
Partners advancing patient-centered research.




Explore Our Satisfied Client Testimonial
In the SEAS study, we found it feasible to remotely capture both physiological data (spirometry) and patient-reported outcomes in a single platform, expanding our ability to conduct COPD research in rural settings

Dr. Sarah Miller
SEAS- Remote Spirometry, Education, and Action for COPD
At AlphaNet, we have over 7,500 persons in Canada and the US who are diagnosed with alpha-1 antitrypsin deficiency participating in our disease management program--our Subscribers. We are excited to use PulManage with wearables to gather data, investigate approaches, and explore opportunities to improve health and quality of life for our subscribers

Mark Delvaux
Mark Delvaux, CEO AlphaNet; Exacerbation prevention in alpha-1 antitrypsin deficiency (AATD)
Building on lessons learned in SEAS, we will leverage PulManage to capture remote spirometry and PROs in a large-scale clinical trial. This will allow us to evaluate functional outcomes and patient experiences concurrently in a flexible and adaptive trial design.

Dr. Sarah Miller
D r. Sarah Miller; RESPfit- Respiratory Muscle FITness Training in COPD
In the SEAS study, we found it feasible to remotely capture both physiological data (spirometry) and patient-reported outcomes in a single platform, expanding our ability to conduct COPD research in rural settings

Dr. Sarah Miller
SEAS- Remote Spirometry, Education, and Action for COPD
Building on lessons learned in SEAS, we will leverage PulManage to capture remote spirometry and PROs in a large-scale clinical trial. This will allow us to evaluate functional outcomes and patient experiences concurrently in a flexible and adaptive trial design.

Dr. Sarah Miller
D r. Sarah Miller; RESPfit- Respiratory Muscle FITness Training in COPD